serine/ threonine exchanger transporter
function
exchange of serine and threonine
product
serine/ threonine exchanger transporter
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.4|Transporters/ other] → [category|SW 1.2.4.1|Amino acid transporters] → [category|SW 1.2.4.1.4|APC superfamily][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]Gene
Coordinates
1,351,375 → 1,352,691
The protein
Protein family
[SW|amino acid-polyamine-organocation (APC) superfamily] (according to UniProt)Structure
[PDB|6F34] (from Geobacillus kaustophilus, 25% identity) [pubmed|29416041][SW|Localization]
membraneExpression and Regulation
Operons
genes
[gene|BCED6015E8CD17F94E9D0BC6CFEB15BF42F890A5|steT]
description
[Pubmed|22383849]
regulation
expression activated by glucose (4.2 fold) [Pubmed|12850135]view in new tabBiological materials
Mutant
GP2378 ∆''[gene|BCED6015E8CD17F94E9D0BC6CFEB15BF42F890A5|steT]'' ::''cat'', available in [SW|Jörg Stülke]'s labGP2945 ∆''[gene|BCED6015E8CD17F94E9D0BC6CFEB15BF42F890A5|steT]'' ::''kan'', available in [SW|Jörg Stülke]'s labMGNA-A736 (ykbA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/736 NBRP B. subtilis, Japan]BKE12860 (Δ[gene|BCED6015E8CD17F94E9D0BC6CFEB15BF42F890A5|steT]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE12860 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTCCTTAACCTCCTATG, downstream forward: _UP4_TGATAAAACGGTTCCCTTGTBKK12860 (Δ[gene|BCED6015E8CD17F94E9D0BC6CFEB15BF42F890A5|steT]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK12860 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTCCTTAACCTCCTATG, downstream forward: _UP4_TGATAAAACGGTTCCCTTGTExpression vector
pGP2281: expression of ''steT'' by [SW|pBQ200] in ''B. subtilis'', available in [SW|Jörg Stülke]'s lablacZ fusion
pGP2275 (in [protein|search|pAC5]) (GP2962), available in [SW|Jörg Stülke]'s labReferences
17344220,12850135,19419962,20610400,26976827,29416041